Rx · Prescription required
Orforglipron
Foundayo®
FDA-approved in April 2026 for chronic weight management in adults with obesity or overweight — the first small-molecule GLP-1 that can be taken at any time of day, with or without food.
- Drug class
- Oral non-peptide GLP-1 receptor agonist
- How it is given
- Once-daily tablet
- Prescription
- Required
- Dispensed by
- DiRx Inc. · licensed pharmacy
FDA status: Foundayo® and the other brand-name versions listed are FDA-approved medicines. Generic versions, where available, are FDA-approved equivalents.
Locked
Pricing is shared after you speak with our team and a licensed doctor approves treatment. Clinics see pricing after account verification.
Important safety information
Orforglipron is a prescription medicine. It is not right for everyone: personal or family history of medullary thyroid carcinoma or MEN 2; pregnancy; history of pancreatitis; people who already take another GLP-1 medicine. Tell your doctor about every condition you have and every medicine and supplement you take.
Common side effects are described below. Stop and seek care for any severe or unexpected reaction. This page is education, not medical advice; your doctor and pharmacist give the instructions for your treatment.
How to get started
- Message us on WhatsApp or call (954) 420-7747.
- Talk with a licensed doctor, who reviews your health history and decides if this medicine is right for you.
- If prescribed, our team shares pricing and a licensed pharmacy fills your order.
Plain-language guide
Orforglipron, explained by our clinical team
What it is
Orforglipron is not a peptide. It is a small molecule designed to switch on the GLP-1 receptor the same way the injectable medicines do, but it survives digestion without special timing rules.
That makes it the most convenient GLP-1 option so far: one tablet, any time, no fasting window, no refrigeration. It is new, so our doctors review the prescribing information carefully with every patient.
FDA-approved uses
- Chronic weight management in adults with obesity, or overweight with at least one weight-related condition, alongside diet and exercise
Our doctors prescribe for approved uses. Any other use is a decision made only by your doctor, for you, after evaluation.
How it is taken
One tablet once a day, with or without food. Treatment starts at a low dose and is raised every four weeks or so as tolerated.
What to expect
Reduced appetite and earlier fullness are the main effects. Nausea, vomiting, constipation and diarrhea are common in the first weeks, especially at each dose step.
Who should not take it
- Personal or family history of medullary thyroid carcinoma or MEN 2
- Pregnancy
- History of pancreatitis
- People who already take another GLP-1 medicine
Questions we hear
Is Foundayo® a peptide?
No. It is a small molecule, which is why it has no food or timing restrictions.
How does it compare to semaglutide?
Trials showed meaningful weight loss; head-to-head answers depend on dose and population. Your doctor will explain the current evidence.
Is it available through EKO Labs?
Availability depends on physician approval and pharmacy supply, which our team confirms during your consultation.
Real molecular structure
The molecule: Orforglipron
Drag to rotate. Every atom and bond below comes from the public PubChem database of the U.S. National Institutes of Health; nothing is drawn by AI.
- Formula
- C48H48F2N10O5
- Molar mass
- 883.0 g/mol
- Heavy atoms
- 113
- PubChem CID
- 137319706 ↗
Source: PubChem, National Library of Medicine (public domain).
Watch & learn
Videos: how it works and how it is used
Independent videos from doctors, hospitals and health educators on YouTube. They are for general education; your doctor gives the instructions for your treatment.
How to use an Ozempic (semaglutide) Pen
Drugs.com · YouTubeOzempic is a game-changer. Here’s how it works.
Vox · YouTubeWhat Ozempic & Weight Loss Drugs Really Do to the Body
Institute of Human Anatomy · YouTubeEndocrinologist shares MUST KNOW tips when starting RYBELSUS
Dr. Akshay Jain · YouTubeOther treatments
Semaglutide
Ozempic® · Wegovy® · Rybelsus®FDA-approved for type 2 diabetes (Ozempic®, Rybelsus®) and for chronic weight management and cardiovascular risk reduction in eligible adults (Wegovy®).
Price after approval
Tirzepatide
Mounjaro® · Zepbound®FDA-approved for type 2 diabetes (Mounjaro®) and for chronic weight management and obstructive sleep apnea in adults with obesity (Zepbound®).
Price after approval
Liraglutide
Victoza® · Saxenda®FDA-approved for type 2 diabetes (Victoza®) and chronic weight management (Saxenda®); generic versions are now available.
Price after approval
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