Updated 2026-09-29 · Reviewed for accuracy by the EKO Labs team. Educational only; not medical advice.
Most side effects of GLP-1 medicines are mild and affect the stomach. Some are rare but serious. Knowing the difference helps you act early.
Common side effects
- Nausea, especially at the start or after a dose increase
- Diarrhea or constipation
- Vomiting
- Reduced appetite
- Stomach discomfort or bloating
Call your doctor if you have
- Vomiting or diarrhea that does not stop, or signs of dehydration
- Pain in the upper right belly, fever or yellow skin or eyes (possible gallbladder problems)
- A lump or swelling in the neck, trouble swallowing or hoarseness
- Changes in vision if you have diabetes
Get emergency care for
- Severe stomach pain that may spread to your back (possible pancreatitis)
- Signs of a serious allergic reaction: swelling of the face or throat, trouble breathing
In an emergency, call 911. This guide is not a complete list. Always read the medication guide that comes with your prescription.
Have questions about your situation?
Talk to our team. A licensed doctor makes every medical decision.
