Updated 2026-09-29 · Reviewed for accuracy by the EKO Labs team. Educational only; not medical advice.
Hypoactive sexual desire disorder (HSDD) is a persistent lack of sexual desire that causes distress and is not explained by another medical condition, a medicine, or relationship problems.
Is it common?
Low desire is one of the most common sexual concerns women report. It is a medical topic, and it is worth discussing with a doctor.
Treatment options
Treatment often starts with looking at possible causes: stress, sleep, other medicines, hormonal changes or relationship factors. For some premenopausal women with acquired, generalized HSDD, doctors may consider an FDA-approved medicine such as bremelanotide (Vyleesi®), an injection used as needed before sexual activity.
Safety
Bremelanotide can cause nausea, flushing and headache, and a temporary rise in blood pressure. It is not for people with uncontrolled high blood pressure or known heart disease, and it is not approved for men or postmenopausal women.
Talk to our team. A licensed doctor makes every medical decision.
