Rx · Prescription required

Flibanserin

Addyi®

FDA-approved for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) not caused by another condition, relationship problem or medicine.

Drug class: Serotonin 1A agonist / 2A antagonist
How it is given: Tablet, once nightly
Prescription: Required
Dispensed by: DiRx Inc. · licensed pharmacy

FDA status: Addyi® and the other brand-name versions listed are FDA-approved medicines. Generic versions, where available, are FDA-approved equivalents.

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Pricing is shared after you speak with our team and a licensed doctor approves treatment. Clinics see pricing after account verification.

Talk to our team Call (954) 420-7747

Important safety information

Flibanserin is a prescription medicine. It is not right for everyone: drinking alcohol within two hours before or after the dose (or at all, depending on amount); liver impairment; taking strong CYP3A4 inhibitors such as some antifungals and antibiotics. Tell your doctor about every condition you have and every medicine and supplement you take.

Common side effects are described below. Stop and seek care for any severe or unexpected reaction. This page is education, not medical advice; your doctor and pharmacist give the instructions for your treatment.

How to get started

Message us on WhatsApp or call (954) 420-7747.
Talk with a licensed doctor, who reviews your health history and decides if this medicine is right for you.
If prescribed, our team shares pricing and a licensed pharmacy fills your order.

Plain-language guide

Flibanserin, explained by our clinical team

What it is

Flibanserin is a daily, non-hormonal tablet that acts on serotonin and dopamine signaling in the brain to rebalance sexual desire. It is the oral alternative to the as-needed injection bremelanotide.

Because alcohol with flibanserin can cause severe low blood pressure and fainting, there are strict rules about drinking, which our doctors go over before prescribing.

FDA-approved uses

Hypoactive sexual desire disorder in premenopausal women

Our doctors prescribe for approved uses. Any other use is a decision made only by your doctor, for you, after evaluation.

How it is taken

One tablet at bedtime every night. If no improvement is seen after eight weeks, treatment is stopped.

What to expect

A gradual increase in desire over weeks. Dizziness, sleepiness, nausea and dry mouth are common; taking it at bedtime limits them.

Who should not take it

Drinking alcohol within two hours before or after the dose (or at all, depending on amount)
Liver impairment
Taking strong CYP3A4 inhibitors such as some antifungals and antibiotics

Questions we hear

Can I drink at all?

Small amounts are allowed only with a gap of at least two hours before the bedtime dose; your doctor will explain the current label rules.

How is it different from Vyleesi®?

Addyi® is a daily tablet; Vyleesi® is an injection taken before sexual activity.

Does it work after menopause?

It is approved for premenopausal women only.

Real molecular structure

The molecule: Flibanserin

Drag to rotate. Every atom and bond below comes from the public PubChem database of the U.S. National Institutes of Health; nothing is drawn by AI.

3D conformer — drag to rotateCNOS

Formula: C20H21F3N4O
Molar mass: 390.4 g/mol
Heavy atoms: 28
PubChem CID: 6918248 ↗

Source: PubChem, National Library of Medicine (public domain).

Watch & learn

Videos: how it works and how it is used

Independent videos from doctors, hospitals and health educators on YouTube. They are for general education; your doctor gives the instructions for your treatment.

How to use