Rx · Prescription required

Rimegepant

Nurtec® ODT

FDA-approved both for acute treatment of migraine and for preventive treatment of episodic migraine in adults — the only medicine approved for both.

Drug class: CGRP receptor antagonist (gepant)
How it is given: Dissolving tablet, as needed or every other day
Prescription: Required
Dispensed by: DiRx Inc. · licensed pharmacy

FDA status: Nurtec® ODT and the other brand-name versions listed are FDA-approved medicines. Generic versions, where available, are FDA-approved equivalents.

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Pricing is shared after you speak with our team and a licensed doctor approves treatment. Clinics see pricing after account verification.

Talk to our team Call (954) 420-7747

Important safety information

Rimegepant is a prescription medicine. It is not right for everyone: use with strong CYP3A4 inhibitors or strong P-gp inhibitors; severe liver impairment; end-stage kidney disease. Tell your doctor about every condition you have and every medicine and supplement you take.

Common side effects are described below. Stop and seek care for any severe or unexpected reaction. This page is education, not medical advice; your doctor and pharmacist give the instructions for your treatment.

How to get started

Message us on WhatsApp or call (954) 420-7747.
Talk with a licensed doctor, who reviews your health history and decides if this medicine is right for you.
If prescribed, our team shares pricing and a licensed pharmacy fills your order.

Plain-language guide

Rimegepant, explained by our clinical team

What it is

Rimegepant is a fast-dissolving tablet that blocks CGRP. Taken at onset it stops attacks; taken every other day it reduces how many attacks happen.

For people with frequent migraines who want one medicine that does both jobs, it simplifies treatment considerably.

FDA-approved uses

Acute treatment of migraine with or without aura
Preventive treatment of episodic migraine

Our doctors prescribe for approved uses. Any other use is a decision made only by your doctor, for you, after evaluation.

How it is taken

Place one tablet on or under the tongue; it dissolves without water. Acute: one dose per 24 hours. Prevention: one dose every other day.

What to expect

Pain relief within two hours for attacks, and fewer migraine days per month with preventive use. Nausea and stomach pain are the main side effects.

Who should not take it

Use with strong CYP3A4 inhibitors or strong P-gp inhibitors
Severe liver impairment
End-stage kidney disease

Questions we hear

Can I use it for both at once?

Yes — the every-other-day schedule still allows an acute dose on the off days as directed.

Is it better than Ubrelvy®?

They are similar for attacks; Nurtec® adds the prevention indication.

Does it cause rebound headache?

No evidence of medication-overuse headache so far.

Real molecular structure

The molecule: Rimegepant

Drag to rotate. Every atom and bond below comes from the public PubChem database of the U.S. National Institutes of Health; nothing is drawn by AI.

3D conformer — drag to rotateCNOS

Formula: C28H28F2N6O3
Molar mass: 534.6 g/mol
Heavy atoms: 39
PubChem CID: 51049968 ↗

Source: PubChem, National Library of Medicine (public domain).

Watch & learn

Videos: how it works and how it is used

Independent videos from doctors, hospitals and health educators on YouTube. They are for general education; your doctor gives the instructions for your treatment.

How to use