Rx · Prescription required

Ubrogepant

Ubrelvy®

FDA-approved for the acute treatment of migraine with or without aura in adults.

Drug class: CGRP receptor antagonist (gepant)
How it is given: Tablet, as needed
Prescription: Required
Dispensed by: DiRx Inc. · licensed pharmacy

FDA status: Ubrelvy® and the other brand-name versions listed are FDA-approved medicines. Generic versions, where available, are FDA-approved equivalents.

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Pricing is shared after you speak with our team and a licensed doctor approves treatment. Clinics see pricing after account verification.

Talk to our team Call (954) 420-7747

Important safety information

Ubrogepant is a prescription medicine. It is not right for everyone: use with strong CYP3A4 inhibitors (some antifungals and antibiotics); severe liver or kidney impairment. Tell your doctor about every condition you have and every medicine and supplement you take.

Common side effects are described below. Stop and seek care for any severe or unexpected reaction. This page is education, not medical advice; your doctor and pharmacist give the instructions for your treatment.

How to get started

Message us on WhatsApp or call (954) 420-7747.
Talk with a licensed doctor, who reviews your health history and decides if this medicine is right for you.
If prescribed, our team shares pricing and a licensed pharmacy fills your order.

Plain-language guide

Ubrogepant, explained by our clinical team

What it is

Ubrogepant belongs to the newest class of migraine medicines. It blocks CGRP, a protein that drives migraine pain, without narrowing blood vessels — so it can be used by people who cannot take triptans because of heart risk.

It has no known risk of medication-overuse headache and causes little drowsiness, making it practical for workdays.

FDA-approved uses

Acute migraine with or without aura in adults

Our doctors prescribe for approved uses. Any other use is a decision made only by your doctor, for you, after evaluation.

How it is taken

One tablet at onset, with or without food; a second dose may be taken at least two hours later, up to 200 mg in 24 hours.

What to expect

Pain freedom or relief within two hours for many people; nausea and sleepiness are the most common side effects and generally mild.

Who should not take it

Use with strong CYP3A4 inhibitors (some antifungals and antibiotics)
Severe liver or kidney impairment

Questions we hear

Gepant or triptan?

Triptans are cheaper and well proven; gepants avoid vascular effects and overuse headache. Your doctor weighs both.

Does it prevent migraine?

Ubrelvy® treats attacks; a related gepant, rimegepant, is also approved for prevention.

Can I combine it with a triptan?

Yes, when needed, under medical direction.

Real molecular structure

The molecule: Ubrogepant

Drag to rotate. Every atom and bond below comes from the public PubChem database of the U.S. National Institutes of Health; nothing is drawn by AI.

3D conformer — drag to rotateCNOS

Formula: C29H26F3N5O3
Molar mass: 549.5 g/mol
Heavy atoms: 40
PubChem CID: 68748835 ↗

Source: PubChem, National Library of Medicine (public domain).

Watch & learn

Videos: how it works and how it is used

Independent videos from doctors, hospitals and health educators on YouTube. They are for general education; your doctor gives the instructions for your treatment.

How to use