Rx · Prescription required

Varenicline

Chantix® (generic available)

FDA-approved as an aid to smoking cessation in adults.

Drug class: Nicotinic receptor partial agonist
How it is given: Tablet, twice daily, 12-week course
Prescription: Required
Dispensed by: DiRx Inc. · licensed pharmacy

FDA status: Chantix® (generic available) and the other brand-name versions listed are FDA-approved medicines. Generic versions, where available, are FDA-approved equivalents.

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Pricing is shared after you speak with our team and a licensed doctor approves treatment. Clinics see pricing after account verification.

Talk to our team Call (954) 420-7747

Important safety information

Varenicline is a prescription medicine. It is not right for everyone: known serious allergic or skin reaction to varenicline; severe kidney impairment without dose adjustment; people who have not decided on a quit date. Tell your doctor about every condition you have and every medicine and supplement you take.

Common side effects are described below. Stop and seek care for any severe or unexpected reaction. This page is education, not medical advice; your doctor and pharmacist give the instructions for your treatment.

How to get started

Message us on WhatsApp or call (954) 420-7747.
Talk with a licensed doctor, who reviews your health history and decides if this medicine is right for you.
If prescribed, our team shares pricing and a licensed pharmacy fills your order.

Plain-language guide

Varenicline, explained by our clinical team

What it is

Varenicline is the most effective single medicine for quitting smoking. It partly stimulates nicotine receptors to ease withdrawal while blocking the reward from any cigarette smoked.

A typical course is 12 weeks, started a week before the quit date, with the option of a second 12 weeks to protect against relapse.

FDA-approved uses

Aid to smoking cessation treatment in adults

Our doctors prescribe for approved uses. Any other use is a decision made only by your doctor, for you, after evaluation.

How it is taken

Start one week before your quit date: 0.5 mg daily for 3 days, then twice daily, then 1 mg twice daily after a meal with a full glass of water.

What to expect

Cigarettes become less satisfying within days; cravings fall over weeks. Nausea, vivid dreams and sleep changes are the most common side effects.

Who should not take it

Known serious allergic or skin reaction to varenicline
Severe kidney impairment without dose adjustment
People who have not decided on a quit date

Questions we hear

Does it affect mood?

The earlier boxed warning was removed in 2016 after a large trial, but any mood change should still be reported.

Can I keep smoking at first?

Yes — the first week overlaps with smoking by design.

Can I use nicotine patches too?

Combination is sometimes used; discuss with your doctor.

Real molecular structure

The molecule: Varenicline

Drag to rotate. Every atom and bond below comes from the public PubChem database of the U.S. National Institutes of Health; nothing is drawn by AI.

3D conformer — drag to rotateCNOS

Formula: C13H13N3
Molar mass: 211.3 g/mol
Heavy atoms: 16
PubChem CID: 5310966 ↗

Source: PubChem, National Library of Medicine (public domain).

Watch & learn

Videos: how it works and how it is used

Independent videos from doctors, hospitals and health educators on YouTube. They are for general education; your doctor gives the instructions for your treatment.

How to use